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  • SULT4A1 Gene - GeneCards | ST4A1 Protein | ST4A1 Antibody
    GeneCards 6 0 Preview is live — explore SULT4A1 in the redesigned release See it now This gene encodes a member of the sulfotransferase family The encoded protein is a brain-specific sulfotransferase believed to be involved in the metabolism of neurotransmitters
  • Association of Sult4A1 SNPs with psychopathology and cognition in . . .
    For the Global Cognitive Summary score, A allele and G allele homozygous patients demonstrated superior scores compared to A G heterozygous patients (p < 02 and p < 01, respectively)
  • SULT4A1 - Wikipedia
    SULT4A1 Sulfotransferase 4A1 is an enzyme that in humans is encoded by the SULT4A1 gene [5][6] This gene encodes a member of the sulfotransferase family The encoded protein is a brain-specific sulfotransferase believed to be involved in the metabolism of neurotransmitters
  • Development and Characterization of SULT4A1 Mutant Mouse Models
    For both mutant lines, heterozygotes appeared to develop normally and were used to breed homozygotes Unexpectedly, homozygous mutants of both lines exhibited severe developmental defects including failure to thrive, difficulty feeding, abnormal gait, poor coordination, and absence seizures
  • Sult4a1 MGI Mouse Gene Detail - MGI:1888971 - sulfotransferase family . . .
    Mice homozygous for a null allele exhibit progressive tremors, ataxia, abnormal gait, absence seizure, porstnatal growth retardation and premature death
  • Sulfotransferase 4A1 Coding Sequence and Protein Structure Are Highly . . .
    Pups of both strains with a homozygous SULT4A1 deletion demonstrated severe and progressive neurological symptoms, including absence seizures, tremors, abnormal gait, ataxia, and a decreased weight gain, leading to postnatal death within 21–25 days compared to wild-type littermates [32]
  • SULT4A1 protein expression summary - The Human Protein Atlas
    Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein (s) are secreted or actually retained in intracellular locations or membrane-attached
  • Sulfotransferase 4A1 Coding Sequence and Protein Structure Are Highly . . .
    SULT4A1 mRNA encodes two variants: (1) the wild type, encoding a 284 amino acid, ~33 kDa protein, and (2) an alternative spliced variant resulting from a 126 bp insert between exon 6 and 7, which introduces a premature stop codon that enhances nonsense-mediated decay





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